Sac Anime happens from the 8th to the 10th in Sacramento, CA. The musical guests include The Slants and Voltaire, and there are many more guests in many other categories.
Animé Los Angeles 6 also happens this same weekend. They have some great Guests of Honor and some good events set up for the convention.
For the weekend Media Con, there is the Twighlight Con in Miami, FL. It runs from the 8th to the 10th, and the estrogen levels should be intense.